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FIS1

fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)

Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

Gene Name: fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
Synonyms: FIS1, CGI-135, FIS1 homolog, HFis1, TPR repeat protein 11, TTC11, H_NH0132A01.6
Target Sequences: NM_016068 NP_057152.2 Q9Y3D6

Publications (1)

1
Proteomic Profiling Revealed Mitochondrial Dysfunction in Photoreceptor Cells under Hyperglycemia. Christie Hang-I Lam, Jimmy Ka-Wai Cheung, Dennis Yan-Yin Tse, Thomas Chuen Lam. International journal of molecular sciences. 2022 November;23: [Full Text Article] [PubMed:36362154] [PMC:PMC9658613] Related Antibodies: LS-C404988.

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Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
FIS1 (9)
No (9)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (8)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (2)
FIS1 Protein - Recombinant Fission 1 By SDS-PAGE
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E. coli
His-T7
17.9 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
FIS1 Protein - 12.5% SDS-PAGE of human FIS1 stained with Coomassie Blue
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Wheat Germ Extract
GST
42.46 kDa
10 µg/$479; 25 µg/$670
FIS1 Protein - Purified recombinant protein FIS1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
16.8 kDa
20 µg/$1,107
FIS1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
293T Cells
Myc-DDK (Flag)
16.8 kDa
20 µg/$150
FIS1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
16.8 kDa
100 µg/$494
FIS1 Protein
Select
E. coli
His
100 µg/$342; 500 µg/$641; 20 µg/$254
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.2 kDa
10 µg/$244; 50 µg/$414
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.2kD
10 µg/$243; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).