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FIG4

FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)

FIG4 belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.

Gene Name: FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
Synonyms: FIG4, ALS11, CMT4J, HSac3, KIAA0274, RP1-249I4.1, DJ249I4.1, FIG4 homolog (S. cerevisiae), SAC3
Target Sequences: NM_014845 NP_055660.1 Q92562

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Antibodies (12)
Proteins (4)
Over-Expression Lysate (2)
Primary (12)
Recombinant (2)
FIG4 (16)
Human (12)
Mouse (10)
Rat (1)
IHC (2)
IHC-P (1)
WB (12)
ELISA (7)
ICC (1)
rabbit (11)
rabbit-new zealand white (1)
IgG (9)
polyclonal pc (12)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (7)
aa846-874 (7)
aa135-430 (1)
No (16)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
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FIG4 Antibody - FIG4 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The FIG4 antibody detected the FIG4 protein (arrow).
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FIG4 Rabbit anti-Human Polyclonal (aa846-874) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
FIG4 Antibody - IHC of paraffin-embedded Breast ca using FIG4 antibody at 1:500 dilution.
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FIG4 Rabbit anti-Human Polyclonal (aa135-430) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
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FIG4 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Rat, Human
IHC, WB
Unconjugated
100 µl/$393
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FIG4 Rabbit anti-Human Polyclonal (aa846-874) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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FIG4 Rabbit anti-Human Polyclonal (aa846-874) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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FIG4 Rabbit anti-Human Polyclonal (aa846-874) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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FIG4 Rabbit anti-Human Polyclonal (aa846-874) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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FIG4 Rabbit anti-Human Polyclonal (aa846-874) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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FIG4 Rabbit anti-Human Polyclonal (aa846-874) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
FIG4 Antibody - Western Blot analysis of 1) mouse liver, 2) HeLa, 3) mouse brain cells using primary antibody diluted at 1:1000 (4°C overnight) . Secondary antibody: Goat Anti-rabbit IgG IRDye 800 (diluted at 1:5000, 25°C, 1 hour).
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FIG4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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FIG4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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FIG4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$357
FIG4 Protein - Purified recombinant protein FIG4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
103.5 kDa
20 µg/$1,107
FIG4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
103.5 kDa
20 µg/$150
FIG4 Protein - 12.5% SDS-PAGE of human FIG4 stained with Coomassie Blue
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Wheat Germ Extract
GST
130 kDa
10 µg/$479; 25 µg/$670
FIG4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
103.5 kDa
100 µg/$494
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).