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Unfortunately, the antibody (ID:24154) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



Fibrinogen

Fibrinogen (factor I) is a glycoprotein in vertebrates that helps in the formation of blood clots. It consists of a linear array of three nodules held together by a very thin thread which is estimated to have a diameter between 8 and 15 Angstrom (Å). The two end nodules are alike but the center one is slightly smaller. Measurements of shadow lengths indicate that nodule diameters are in the range 50 to 70 Angstrom. The length of the dried molecule is 475 ± 25 Angstrom. The fibrinogen molecule is a soluble, large, and complex glycoprotein, 340 kDa plasma glycoprotein, that is converted by thrombin into fibrin during blood clot formation. It has a rod-like shape with dimensions of 9 × 47.5 × 6 nm and it shows a negative net charge at physiological pH (IP at pH 5.2). Fibrinogen is synthesized in the liver by the hepatocytes. The concentration of fibrinogen in the blood plasma is 200–400 mg/dL (normally measured using the Clauss method). During normal blood coagulation, a coagulation cascade activates the zymogen prothrombin by converting it into the serine protease thrombin. Thrombin then converts the soluble fibrinogen into insoluble fibrin strands. These strands are then cross-linked by factor XIII to form a blood clot. FXIIa stabilizes fibrin further by incorporation of the fibrinolysis inhibitors alpha-2-antiplasmin and TAFI (thrombin activatable fibrinolysis inhibitor, procarboxypeptidase B), and binding to several adhesive proteins of various cells. Both the activation of factor XIII by thrombin and plasminogen activator (t-PA) are catalyzed by fibrin. Fibrin specifically binds the activated coagulation factors factor Xa and thrombin and entraps them in the network of fibers, thus functioning as a temporary inhibitor of these enzymes, which stay active and can be released during fibrinolysis.

Fibrinogen Target Details

Target Name: Fibrinogen

Publications (1)

1
A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis. Cordova KN, Willis VC, Haskins K, Holers VM. Journal of immunology (Baltimore, Md. : 1950). 2013 190:1457-65. (WB; Mouse) [PubMed:23319740] Related Antibodies: LS-C129050.

Filtered By: None
Target
fibrinogen (146)
Reactivity
Human (74)
Mouse (33)
Rat (20)
Bovine (3)
Dog (10)
Pig (2)
Rabbit (16)
Application
IHC (27)
IHC-Fr (15)
IHC-P (19)
WB (62)
Flo (1)
Block (1)
DB (8)
ELISA (119)
GS (1)
ICC (8)
ID (18)
IE (18)
IF (15)
IP (1)
RIA (7)
SwELISA (1)
Host
rabbit (38)
mouse (45)
goat (38)
chicken (1)
sheep (24)
Isotype
IgG (58)
IgG1 (33)
IgG1,k (3)
IgG2a (7)
IgG2b (1)
IgM (1)
IgY (1)
Clonality
monoclonal mc (45)
polyclonal pc (101)
Clone
15E11 (1)
15H12 (1)
173602 (1)
1D6 (1)
1F3 (2)
20B2 (1)
23H2 (1)
27C8 (3)
3D1 (1)
3F2 (1)
40F11 (2)
41D9 (1)
5C5 (1)
6G12 (1)
MFB-HB (1)
Format
AP Conjugated (5)
APC Conjugated (4)
Biotin Conjugated (15)
FITC Conjugated (20)
HRP Conjugated (18)
PE Conjugated (5)
Unconjugated (79)
Epitope
Citrullinated (2)
Publications
No (145)
Yes (1)
Showing 1-25 out of 146 results
Fibrinogen Antibody IHC-plus™ LS-B2573
Anti-Fibrinogen antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2573 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Sheep Polyclonal (IgG) to Human Fibrinogen
Mouse, Rat, Human
ELISA IF IHC IHC-Fr IHC-P
Unconjugated
Fibrinogen Antibody (FITC) LS-C56206
Anti-Fibrinogen antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2573 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Sheep Polyclonal to Human Fibrinogen
Mouse, Rat, Human
ELISA IF IHC IHC-Fr IHC-P
FITC Conjugated
Fibrinogen Antibody IHC-plus™ LS-B381
Anti-Fibrinogen antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B381 dilution 1:500.

Goat Polyclonal to Human Fibrinogen
Human
ELISA IHC IHC-P WB
Unconjugated
Fibrinogen Antibody IHC-plus™ LS-B697
Anti-Fibrinogen antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B697 concentration 5 ug/ml.
Anti-Fibrinogen antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B697 concentration 5 ug/ml.

Goat Polyclonal to Human Fibrinogen
Human
ELISA IHC IHC-P WB
Unconjugated
Fibrinogen Antibody LS-C150799

Rabbit Polyclonal (IgG) to Mouse Fibrinogen
Mouse, Rat
ELISA IHC IHC-Fr IHC-P WB
Unconjugated
Fibrinogen Antibody (clone 27C8) LS-C52057

Mouse Monoclonal [clone 27C8] (IgG2a) to Human Fibrinogen
Human
ELISA WB
Unconjugated
Fibrinogen Antibody LS-C109177

Rabbit Polyclonal (IgG) to Human Fibrinogen
Human
ELISA WB
Unconjugated
Fibrinogen Antibody LS-C129050

Rabbit Polyclonal to Mouse Fibrinogen
Mouse
ELISA WB
Unconjugated
Fibrinogen Antibody IHC-plus™ LS-B5249
Anti-Fibrinogen antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5249 concentration 5 ug/ml.
Anti-Fibrinogen antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5249 concentration 5 ug/ml.

Rabbit Polyclonal (IgG) to Human Fibrinogen
Human
ELISA IHC IHC-P WB
Unconjugated
Fibrinogen Antibody (HRP) LS-C109181

Rabbit Polyclonal (IgG) to Human Fibrinogen
Human
ELISA
HRP Conjugated
Fibrinogen Antibody (Biotin) LS-C109179

Rabbit Polyclonal (IgG) to Human Fibrinogen
Human
ELISA WB
Biotin Conjugated
Fibrinogen Antibody (HRP) LS-C147232

Goat Polyclonal to Human Fibrinogen
Human
ELISA IHC WB
HRP Conjugated
Fibrinogen Antibody (clone 5C5) IHC-plus™ LS-B7075
Anti-Fibrinogen antibody IHC of human small intestine, intravascular plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7075 dilution 1:200.
Western blot Image

Mouse Monoclonal [clone 5C5] (IgG1,k) to Human Fibrinogen
Human
ELISA IHC IHC-P WB
Unconjugated
Fibrinogen Antibody (clone MFB-HB) LS-C134840

Mouse Monoclonal [clone MFB-HB] (IgM) to Human Fibrinogen
Human
ELISA IF IHC IHC-Fr
Unconjugated
Fibrinogen Antibody LS-C147228

Goat Polyclonal to Human Fibrinogen
Human
ELISA IF IHC
Unconjugated
Fibrinogen Antibody LS-C96078

Rabbit Polyclonal to Human Fibrinogen
Rabbit, Human
Block ELISA IF
Unconjugated
Fibrinogen Antibody LS-C23567

Mouse Monoclonal (IgG1)
Human
ELISA SwELISA WB
Unconjugated
Fibrinogen Antibody LS-C109182

Rabbit Polyclonal (IgG) to Human Fibrinogen
Human
ELISA WB
Unconjugated
Fibrinogen Antibody (clone 1F3) LS-C85115

Mouse Monoclonal [clone 1F3] (IgG1)
ELISA WB
Unconjugated
Fibrinogen Antibody (FITC) LS-C147231

Goat Polyclonal to Human Fibrinogen
Human
ELISA IF
FITC Conjugated
Fibrinogen Antibody (Biotin) LS-C147230

Goat Polyclonal to Human Fibrinogen
Human
ELISA IHC
Biotin Conjugated
Fibrinogen Antibody (FITC) LS-C95293

Rabbit Polyclonal to Human Fibrinogen
Human
IF
FITC Conjugated
Fibrinogen Antibody (FITC) LS-C346567

Goat Polyclonal to Mouse Fibrinogen
Mouse
ELISA ICC ID IF IHC IHC-Fr
FITC Conjugated
Fibrinogen Antibody LS-C315781

Goat Polyclonal to Human Fibrinogen
Human
ELISA Flo ID IHC IP WB
Unconjugated
Fibrinogen Antibody (Biotin) LS-C299207

Rabbit Polyclonal (IgG) to Bovine Fibrinogen
Bovine
WB
Biotin Conjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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