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FHOS / FHOD1

formin homology 2 domain containing 1

FHOS / FHOD1 is a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines.

Gene Name: formin homology 2 domain containing 1
Synonyms: FHOD1, FHOS, FHOS1
Target Sequences: NM_013241 NP_037373.2 Q9Y613

Publications (1)

1
Active FHOD1 promotes the formation of functional actin stress fibers. Xuemeng Shi, Shuangshuang Zhao, Jinping Cai, Gary Wong, Yaming Jiu. The Biochemical journal. 2019 Oct;476:2953-2963. [Full Text Article] [PubMed:31657439] Related Antibodies: LS-C321389.

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
FHOS / FHOD1 (4)
No (4)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
FHOS / FHOD1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
FHOS / FHOD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
126.4 kDa
100 µg/$494
FHOS / FHOD1 Protein - Purified recombinant protein FHOD1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
126.4 kDa
20 µg/$1,107
FHOS / FHOD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
126.4 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).