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FGL1 / Hepassocin

fibrinogen-like 1

Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.

Gene Name: fibrinogen-like 1
Synonyms: FGL1, Fibrinogen-like 1, Hepassocin, HFREP-1, HFREP1, HP-041, LFIRE-1, Fibrinogen-like protein 1, LFIRE1
Target Sequences: NM_004467 NP_004458.3 Q08830

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).