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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FGG / Fibrinogen Gamma

fibrinogen gamma chain

Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Gene Name: fibrinogen gamma chain
Synonyms: FGG, Fibrinogen gamma-b chain, Fibrinogen gamma chain, Fibrinogen, gamma polypeptide
Target Sequences: NM_021870 NP_068656.2 P02679

Publications (1)

1
Compression force sensing regulates integrin aIIbß3adhesive function on diabetic platelets. Ju L, McFadyen JD, Al-Daher S, Alwis I, Chen Y, Tønnesen LL, Maiocchi S, Coulter B, Calkin AC, Felner EI, Cohen N, Yuan Y, Schoenwaelder SM, Cooper ME, Zhu C, Jackson SP. Nature communications. 2018 March;9:1087. (Human) [Full Text Article] [PubMed:29540687] [PMC:PMC5852038] Related Antibodies: LS-C418056.

Filtered by: None
Type
Over-Expression Lysate (3)
Recombinant (11)
Target
FGG / Fibrinogen Gamma (14)
Tag
GST,N-terminus (1)
His (6)
His + T7 (1)
His, N-Terminal (2)
Myc + DDK (4)
Species
Bovine (1)
Chicken (1)
Human (8)
Mouse (1)
Rat (1)
Source
293T Cells (1)
E. coli (8)
Eukaryotic cells (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purification
Purified (7)
Low Endotoxin Level
Low endotoxin level (1)
Publications
No (14)
Showing 1-14 of 14 results

Human FGG / Fibrinogen Gamma Protein (Recombinant GST,N-terminus) (aa31-130) - LS-G58567
Wheat Germ Extract
GST,N-terminus
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE Stained with Coomassie Blue.

Bovine FGG / Fibrinogen Gamma Protein (Recombinant His + T7) (aa168-444) - LS-G24881
E. coli
His + T7
35.1 kDa
10µg  $295.00; 50µg  $495.00; 100µg  $695.00; 200µg  $1,005.00; 1mg  $2,580.00; 500µg  $1,140.00
Recombinant  Fibrinogen Gamma By SDS-PAGE

FGG / Fibrinogen Gamma Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G99058
HEK 293 Cells
Myc + DDK
49.5 kDa
100µg  $365.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human FGG / Fibrinogen Gamma Protein (Recombinant His) - LS-G3166
E. coli
His
20µg 0.5mg/ml  $315.00; 100µg 0.5mg/ml  $695.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

FGG / Fibrinogen Gamma Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G110586
HEK 293 Cells
Myc + DDK
48.4 kDa
100µg  $475.00

Human FGG / Fibrinogen Gamma Protein (Recombinant His, N-Terminal) (Lys166-Asn416) - LS-G132915
Eukaryotic cells
His, N-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
30kDa
10µg  $275.00; 50µg  $435.00; 200µg  $830.00; 100µg  $665.00; 1mg  $2,475.00; 500µg  $1,095.00
Eukaryotic Fibrinogen Gamma (FGg) by SDS-PAGE

Chicken FGG / Fibrinogen Gamma Protein (Recombinant His) (aa27-435) - LS-G14944
E. coli
His
48.5 kDa
10µg  $245.00; 50µg  $385.00; 100µg  $465.00; 200µg  $665.00; 1mg  $1,725.00; 500µg  $770.00
Recombinant Fibrinogen Gamma By SDS-PAGE

Human FGG / Fibrinogen Gamma Protein (Recombinant His) (aa166-416) - LS-G14947
E. coli
His
29.9 kDa
10µg  $235.00; 50µg  $355.00; 100µg  $425.00; 200µg  $590.00; 1mg  $1,500.00; 500µg  $665.00

Human FGG / Fibrinogen Gamma Protein (Recombinant His) (aa64-268) - LS-G14949
E. coli
His
29.8 kDa
10µg  $285.00; 50µg  $415.00; 100µg  $560.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Rat FGG / Fibrinogen Gamma Protein (Recombinant His) (aa170-429) - LS-G14950
E. coli
His
31.1 kDa
10µg  $255.00; 50µg  $405.00; 100µg  $495.00; 200µg  $740.00; 1mg  $1,890.00; 500µg  $845.00

Mouse FGG / Fibrinogen Gamma Protein (Recombinant His) (aa168-405) - LS-G14948
E. coli
His
28.6 kDa
10µg  $275.00; 50µg  $455.00; 100µg  $590.00; 200µg  $875.00; 1mg  $2,235.00; 500µg  $995.00
Recombinant Fibrinogen Gamma By SDS-PAGE

Human FGG / Fibrinogen Gamma Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G75912
293T Cells
Myc + DDK
49.5 kDa
20µg  $195.00

Human FGG / Fibrinogen Gamma Protein (Recombinant His, N-Terminal) (aa27-437) - LS-G134646
E. coli
His, N-Terminal
48.9kDa
2µg  $195.00; 10µg  $255.00; 100µg  $1,260.00

Human FGG / Fibrinogen Gamma Protein (Recombinant Myc + DDK) (Full Length) - LS-G65625
HEK 293 Cells
Myc + DDK
46.4 kDa
20µg  $890.00
Purified recombinant protein FGG was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Showing 1-14 of 14 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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