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FGF4

fibroblast growth factor 4

FGF4 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

Gene Name: fibroblast growth factor 4
Family/Subfamily: HBGF , not assigned-HBGF
Synonyms: FGF4, Fibroblast growth factor 4, FGF-4, Hst, HSTF-1, Kaposi sarcoma oncogene, K-FGF, KFGF, HBGF-4, HST-1, Oncogene HST, HSTF1, KS3, Transforming protein KS3
Target Sequences: NM_002007 NP_001998.1 P08620

☰ Filters
Products
Proteins (15)
Over-Expression Lysate (2)
Recombinant (13)
FGF4 (15)
Animal-free (1)
No (15)
His-GST (1)
Myc-DDK (Flag) (2)
Bovine (1)
Human (12)
Mouse (1)
293T Cells (1)
E. coli (13)
HEK 293 Cells (1)
Purified (4)
Low endotoxin level (11)
Biologically active (7)
Animal-free (1)
FGF4 Protein - The ED50 as determined by the dose-dependent stimulation of mouse fibroblasts was <0.2 ng/ml
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~20 kDa
25 µg/$291; 100 µg/$452; 1 mg/$2,851
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.9kD
10 µg/$288; 50 µg/$442; 500 µg/$1,377; 1 mg/$1,765
FGF4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.9 kDa
20 µg/$150
FGF4 Protein - Recombinant Fibroblast Growth Factor 4 By SDS-PAGE
Select
E. coli
His-GST
45.1 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
Select
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
19.4 kDa (SDS-PAGE)
5 µg/$253; 25 µg/$296; 100 µg/$453
FGF4 Protein
Select
E. coli
None
Less than 0.1 EU/µg protein (determined by LAL method).
19.4 kDa
100 µg/$677
FGF4 Protein - NIH3T3 proliferation induced by human FGF-4.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 153 amino acid recombinant protein has a predicted molecular mass of approximately 19.7 kD. The non-reduced and DTT-reduced protein migrates at approximately 19.7 kD by SDS-PAGE. The predicted N-terminal amino acid is Serine.
25 µg/$352; 100 µg/$738
FGF4 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
16.9 kDa
50 µg/$516; 10 µg/$313; 1 mg/$2,321; 500 µg/$1,666
FGF4 Protein - Recombinant Human FGF-4
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
15.1 kDa
10 µg/$298; 50 µg/$473
FGF4 Protein - Recombinant Mouse Fibroblast Growth Factor 4/FGF-4
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
15.2 kDa
10 µg/$298; 50 µg/$473
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.9 kDa
10 µg/$288; 50 µg/$436
FGF4 Protein
Select
E. coli
None
Biologically active
19.8 kDa
5 µg/$282; 500 µg/$1,747; 100 µg/$957
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
19.7 kDa
5 µg/$268; 25 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
5 µg/$281; 25 µg/$369
FGF4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
21.9 kDa
100 µg/$494
Viewing 1-15 of 15 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).