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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
FGF4
fibroblast growth factor 4
FGF4 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
| Gene Name: | fibroblast growth factor 4 |
| Family/Subfamily: | HBGF , not assigned-HBGF |
| Synonyms: | FGF4, Fibroblast growth factor 4, FGF-4, Hst, HSTF-1, Kaposi sarcoma oncogene, K-FGF, KFGF, HBGF-4, HST-1, Oncogene HST, HSTF1, KS3, Transforming protein KS3 |
| Target Sequences: | NM_002007 NP_001998.1 P08620 |
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