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FGF21

fibroblast growth factor 21

Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.

Gene Name: fibroblast growth factor 21
Family/Subfamily: HBGF , not assigned-HBGF
Synonyms: FGF21, Fibroblast growth factor 21, FGF-21
Target Sequences: NM_019113 NP_061986.1 Q9NSA1

Publications (4)

1
Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia. Yamanishi K, Maeda S, Kuwahara-Otani S, Hashimoto T, Ikubo K, Mukai K, Nakasho K, Gamachi N, El-Darawish Y, Li W, Okuzaki D, Watanabe Y, Yamanishi H, Okamura H, Matsunaga H. Journal of translational medicine. 2018 November;16:314. [Full Text Article] [PubMed:30453990] [PMC:PMC6245626] Related Antibodies: LS-B5864.
2
Relationship of HIV Status and Fatigue, Cardiorespiratory Fitness, Myokines, and Physical Activity. Allison R Webel, Trevor Jenkins, Christopher T Longenecker, Marianne Vest, Christine Horvat Davey, Jackson Currie, Rebecca Darrah, Paul Litman, Vitor Hugo Fernando de Oliveira, Richard A Josephson. The journal of the Association of Nurses in AIDS Care : JANAC. 2019 June;30:392-404. [Full Text Article] [PubMed:31241504] [PMC:PMC7179736]
3
Reversal of obesity-induced hypertriglyceridemia by (R)- alpha -lipoic acid in ZDF (fa/fa) rats. Yi X, Pashaj A, Xia M, Moreau R. Biochemical and biophysical research communications. 2013 Sep;439:390-5. [Full Text Article] [PubMed:23994635] Related Antibodies: LS-B5864.
4
Astragalus polysaccharides affect insulin resistance by regulating the hepatic SIRT1-PGC-1a/PPARa-FGF21 signaling pathway in male Sprague Dawley rats undergoing catch-up growth. Gu C, Zeng Y, Tang Z, Wang C, He Y, Feng X, Zhou L. Molecular medicine reports. 2015 12:6451-60. (WB; Rat) [Full Text Article] [PubMed:26323321] [PMC:PMC4626146] Related Antibodies: LS-B5864.
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ELISA Kits (35)
Competitive EIA (1)
Sandwich (29)
Sandwich CLIA (5)
FGF21 (35)
Human (9)
Mouse (10)
Rat (6)
Bovine (2)
Chicken (1)
Guinea pig (1)
Monkey (1)
Pig (4)
Rabbit (1)
12 x 8-Well Microstrips (2)
96-Well Microplate (8)
96-Well Strip Plate (24)
No (34)
Yes (1)
Cell Culture Supernatants (12)
Cell Lysates (8)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (31)
Serum (32)
Tissue Homogenates (14)
FGF21 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FGF21 ELISA Kit
Select
Sandwich
96-Well Microplate
Pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
FGF21 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$968
FGF21 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
2.74 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$968
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
23.5 - 1500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
FGF21 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$602
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,041
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$958
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
FGF21 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$646
FGF21 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$856
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$795
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FGF21 ELISA Kit
Select
Sandwich
Rat
31.2 - 2000 pg/ml
Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$795
FGF21 ELISA Kit
Select
Sandwich
96-Well Microplate
Rabbit
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$669
FGF21 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FGF21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
FGF21 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).