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FGF1 / Acidic FGF

fibroblast growth factor 1 (acidic)

FGF1 / Acidic FGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.

Gene Name: fibroblast growth factor 1 (acidic)
Family/Subfamily: HBGF , not assigned-HBGF
Synonyms: FGF1, AFGF, Endothelial cell growth factor, Fibroblast growth factor 1, FGFA, ECGFB, HBGF-1, GLIO703, ECGF, ECGF-beta, ECGFA, FGF-1, FGF-alpha, HBGF1
Target Sequences: X59065 P05230 P05230

Publications (1)

1
Anti-inflammatory effects of saxagliptin and vildagliptin against doxorubicin-induced nephrotoxicity in rats: attenuation of NLRP3 inflammasome up-regulation and tubulo-interstitial injury. Rasha Ezzat Mostafa, Azza Hassan Morsi, Gihan Farag Asaad. Research in pharmaceutical sciences. 2021 Aug;16:547-558. [Full Text Article] [PubMed:34522201] [PMC:PMC8407158]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).