FGB / Fibrinogen Beta Chain

fibrinogen beta chain

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

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Proteins (11)

Type

Over-Expression Lysate (2)

Recombinant (9)

Target

FGB / Fibrinogen Beta Chain (11)

Publications

No (11)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His (3)

His, N-Terminal (1)

His-S (3)

Myc-DDK (Flag) (2)

Species

Bovine (1)

Human (7)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (8)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

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Human FGB / Fibrinogen Beta Chain Protein (Recombinant His, N-Terminal) (aa45-491) - LS-G13483

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

52.3 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Rat FGB / Fibrinogen Beta Chain Protein (Recombinant His-S) (aa33-479) - LS-G13486

Source:

E. coli

Tag:

His-S

Molecular Weight:

56.4 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human FGB / Fibrinogen Beta Chain Protein (Recombinant His) - LS-G3307

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human FGB / Fibrinogen Beta Chain Protein (Recombinant His-S) (aa29-491) - LS-G13485

Source:

E. coli

Tag:

His-S

Molecular Weight:

58.2 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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FGB / Fibrinogen Beta Chain Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116122

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.92 kDa

Price:

100 µg/$494

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Human FGB / Fibrinogen Beta Chain Protein (Recombinant His) (aa29-118) - LS-G24244

Source:

E. coli

Tag:

His

Molecular Weight:

10.8 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Human FGB / Fibrinogen Beta Chain Protein (Recombinant 6His, N-terminus) (aa45-491) - LS-G56262

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human FGB / Fibrinogen Beta Chain Protein (Recombinant GST, N-terminus) (aa392-491) - LS-G58553

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human FGB / Fibrinogen Beta Chain Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85800

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.92 kDa

Price:

20 µg/$150

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Bovine FGB / Fibrinogen Beta Chain Protein (Recombinant His-S) (aa49-495) - LS-G13478

Source:

E. coli

Tag:

His-S

Molecular Weight:

56.7 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Mouse FGB / Fibrinogen Beta Chain Protein (Recombinant His) (aa35-481) - LS-G13487

Source:

E. coli

Tag:

His

Molecular Weight:

52.3 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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