FGA / Fibrinogen Alpha

fibrinogen alpha chain

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

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Products

Proteins (11)

Type

Over-Expression Lysate (2)

Recombinant (9)

Target

FGA / Fibrinogen Alpha (11)

Publications

No (11)

Tag

GST (1)

His (6)

His-S (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Bovine (1)

Human (5)

Mouse (2)

Rat (2)

Source

293T Cells (1)

E. coli (8)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human FGA / Fibrinogen Alpha Protein (Recombinant His-S) (aa124-214) - LS-G13400

Source:

E. coli

Tag:

His-S

Molecular Weight:

16.5 kDa

Price:

10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646

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FGA / Fibrinogen Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110587

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.6 kDa

Price:

100 µg/$710

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Human FGA / Fibrinogen Alpha Protein (Recombinant His) (aa36-218) - LS-G20733

Source:

E. coli

Tag:

His

Molecular Weight:

25.2 kD

Price:

100 µg/$420; 20 µg/$323; 1 mg/$1,355

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Human FGA / Fibrinogen Alpha Protein (Recombinant GST) (Full Length) - LS-G28460

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

49.72 kDa

Price:

10 µg/$479; 25 µg/$670

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Bovine FGA / Fibrinogen Alpha Protein (Recombinant His) (aa39-615) - LS-G24219

Source:

E. coli

Tag:

His

Molecular Weight:

66.8 kDa

Price:

10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225

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Human FGA / Fibrinogen Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75911

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.6 kDa

Price:

20 µg/$215

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Human FGA / Fibrinogen Alpha Protein (Recombinant His) (aa562-629) - LS-G140956

Source:

E. coli

Sequence Length:

67 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

7.48 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Mouse FGA / Fibrinogen Alpha Protein (Recombinant His) (aa357-556) - LS-G13402

Source:

E. coli

Tag:

His

Molecular Weight:

23.3 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Rat FGA / Fibrinogen Alpha Protein (Recombinant His) (aa554-655) - LS-G13403

Source:

E. coli

Tag:

His

Molecular Weight:

11.9 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Rat FGA / Fibrinogen Alpha Protein (Recombinant His) (aa77-244) - LS-G13406

Source:

E. coli

Tag:

His

Molecular Weight:

21.1 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Mouse FGA / Fibrinogen Alpha Protein (Recombinant His-T7) (aa34-255) - LS-G13407

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.6 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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