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FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
| Gene Name: | fasciculation and elongation protein zeta 1 (zygin I) |
| Synonyms: | FEZ1, Zygin-1, Zygin I |
| Target Sequences: | NM_005103 NP_005094.1 Q99689 |
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