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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FER

fer (fps/fes related) tyrosine kinase

Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS). Plays a role in synapse organization, trafficking of synaptic vesicles, the generation of excitatory postsynaptic currents and neuron-neuron synaptic transmission. Plays a role in neuronal cell death after brain damage. Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3, but the biological relevance of this depends on cell type and stimulus.

Gene Name: fer (fps/fes related) tyrosine kinase
Family/Subfamily: Protein Kinase , Fes (Fps)
Synonyms: FER, c-fer, Fer kinase, p94-Fer, Phosphoprotein NCP94, PPP1R74, Proto-oncogene c-Fer, TYK3, Tyrosine-protein kinase Fer, p94fer, Tyrosine kinase 3, FerT
Target Sequences: NM_005246 NP_005237.2 P16591

Filtered by: None
Target
FER (55)
Reactivity
Human (46)
Mouse (42)
Rat (16)
Bovine (2)
Dog (4)
Horse (1)
Monkey (1)
Pig (2)
Sheep (1)
Application
IHC (21)
IHC-P (8)
WB (55)
Flo (2)
DB (2)
ELISA (22)
ICC (2)
IF (9)
IP (4)
Peptide-ELISA (5)
Host
rabbit (47)
mouse (8)
Isotype
IgG (32)
IgG1 (6)
IgG1,k (1)
IgG2a,k (1)
Clonality
monoclonal mc (8)
polyclonal pc (47)
Clone
1457CT181.12.17 (1)
1487CT794.8.50 (1)
2358C3a (2)
5D2C4 (2)
Format
AP Conjugated (3)
APC Conjugated (3)
Biotin Conjugated (4)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (33)
Epitope
aa782-811 (8)
aa783-810 (8)
Internal (5)
pTyr402 (4)
340-420 aa (2)
aa400-450 (2)
740-820 aa, C-terminal (1)
Asp798 (1)
C-Terminus (1)
aa371-420 (1)
aa521-536 (1)
aa766-815 (1)
aa797-811 (1)
Publications
No (54)
Yes (1)
Showing 1-25 of 55 results

IHC-plus™ FER Antibody (clone 5D2C4) LS-B3467
Publications (1)
Publications (1)
Mouse Monoclonal [clone 5D2C4] (IgG1) to Human FER
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Anti-FER antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-FER antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

FER Antibody (740-820 aa, C-terminal) LS-C383482
Rabbit Polyclonal (IgG) to Human FER
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of Fer antibody

FER Antibody (clone 5D2C4) LS-C355328
Mouse Monoclonal [clone 5D2C4] (IgG1) to Human FER
Mouse, Human
ICC, IF, IHC, WB
Unconjugated
100µl  $425.00
IHC using FER Antibody (5D2C4)
IF using FER Antibody (5D2C4)

FER Antibody (aa782-811) LS-C99375
Rabbit Polyclonal to Human FER
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
FER Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of FER Antibody with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).

FER Antibody (C-Terminus) LS-C352193
Rabbit Polyclonal to Human FER
Dog, Bovine, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of c-FER staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of c-FER staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

FER Antibody LS-C752752
Rabbit Polyclonal (IgG) to Human FER
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100µg  $375.00

IHC-plus™ FER Antibody (aa400-450) LS-B15119
Rabbit Polyclonal (IgG) to Human FER
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Detection of Human and Mouse FER by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-FER antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

FER Antibody (phospho-Tyr402) LS-C800204
Rabbit Polyclonal (IgG) to Human FER
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Immunofluorescence Image

IHC-plus™ FER Antibody LS-B15570
Rabbit Polyclonal (IgG) to Human FER
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE)

FER Antibody (phospho-Tyr402) LS-C198956
Rabbit Polyclonal (IgG) to Human FER
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain, using FER (Phospho-Tyr402) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of lysates from Jurkat cells treated with starved 24h, using FER (Phospho-Tyr402) Antibody. The lane on the right is blocked with the phospho peptide.

FER Antibody (aa521-536) LS-C313021
Rabbit Polyclonal to Human FER
Sheep, Bovine, Rat, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µg 200µl 0.5mg/ml  $305.00
FER antibody. IHC(P): Human Intestinal Cancer Tissue.
FER antibody. IHC(P): Rat Intestine Tissue.

FER Antibody (340-420 aa) LS-C381374
Rabbit Polyclonal (IgG) to Human FER
Mouse, Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

FER Antibody LS-C800686
Rabbit Polyclonal (IgG) to Human FER
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image

FER Antibody (clone 2358C3a) LS-C342523
Mouse Monoclonal [clone 2358C3a] (IgG1) to Human FER
Mouse, Human
DB, IP, WB
Unconjugated
100µg 100µg/ml  $415.00
Detection of FER by Western blot. Samples: Whole cell lysate from human HeLa (H, 25 ug) and mouse NIH3T3 (M, 25 ug) cells. Predicted molecular weight: 94 kDa
Western blot analysis of immunized recombinant protein, using anti-FER monoclonal antibody.

FER Antibody (phospho-Tyr402) LS-C358983
Rabbit Polyclonal to Human FER
Mouse, Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
30µl 1mg/ml  $215.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $325.00
Immunohistochemical analysis of c-FER (pY402) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of c-FER (pY402) expression in HeLa (A); Jurkat (B); NIH3T3 (C) whole cell lysates.

FER Antibody (aa783-810) LS-C321354
Rabbit Polyclonal (IgG) to Mouse FER
Mouse
ELISA, WB
Unconjugated
200µl  $590.00

FER Antibody (Asp798) LS-C176736
Rabbit Polyclonal to Human FER
Mouse, Rat, Human
IF, WB
Unconjugated
100µl  $345.00
Western blot of Fer (D798) pAb in extracts from HeLa cells.

FER Antibody LS-C190074
Rabbit Polyclonal to Human FER
Mouse, Rat, Human
IHC, WB
Unconjugated
100µg  $650.00

FER Antibody (phospho-Tyr402) LS-C415778
Rabbit Polyclonal to Human FER
Mouse, Human
IHC, WB
Unconjugated
100µg  $305.00
Western blot of Jurkat cell lysate using Phospho-FER(Tyr402) Antibody

FER Antibody (aa797-811) LS-C6775
Mouse Monoclonal (IgG1) to Human FER
Mouse, Dog, Rat, Human
ELISA, WB
Unconjugated
100µg  $815.00

FER Antibody (clone 2358C3a) LS-C184482
Mouse Monoclonal [clone 2358C3a] (IgG1) to Human FER
Mouse, Human
DB, IP, WB
Unconjugated
100µg  $560.00

FER Antibody (clone 1487CT794.8.50) LS-C356277
Mouse Monoclonal [clone 1487CT794.8.50] (IgG2a,k) to Mouse FER
Mouse
Peptide-ELISA, WB
Unconjugated
400µl  $325.00
All lanes : Anti-Fer Antibody at 1:4000 dilution Lane 1: NIH/3T3 whole cell lysates Lane 2: mouse testis lysates Lane 3: mouse liver lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 95 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

FER Antibody (aa782-811) LS-C327368
Rabbit Polyclonal (IgG) to Human FER
Human
ELISA, WB
Unconjugated
200µl  $590.00

FER Antibody LS-C65986
Mouse Monoclonal (IgG1) to Human FER
Mouse, Human
IP, WB
Unconjugated
100µg  $545.00

FER Antibody (clone 1457CT181.12.17) LS-C356265
Mouse Monoclonal [clone 1457CT181.12.17] (IgG1,k) to Human FER
Mouse, Human
Peptide-ELISA, WB
Unconjugated
400µl  $325.00
Western blot of lysates from HeLa, A549, mouse NIH/3T3 cell line (from left to right), using FER antibody diluted at 1:2000 at each lane. A goat anti-mouse IgG H&L (HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.
Showing 1-25 of 55 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).