FDPS

farnesyl diphosphate synthase

FDPS is an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

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Products

ELISA Kits (2)

Type

Sandwich (2)

Target

FDPS (2)

Reactivity

Human (1)

Rat (1)

Format

96-Well Strip Plate (2)

Publications

No (2)

Sample Type

Cell Lysates (1)

Plasma (1)

Serum (1)

Tissue Homogenates (2)

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Human FDPS (Sandwich ELISA) ELISA Kit - LS-F25450

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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Rat FDPS (Sandwich ELISA) ELISA Kit - LS-F8916

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$893

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