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B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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FCRL4 / IRTA1 / CD307d
Fc receptor-like 4
IRTA1 / FCRL4 is a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.
| Gene Name: | Fc receptor-like 4 |
| Family/Subfamily: | Immune Receptor Translocation-Associated Protein (IRTA) |
| Synonyms: | FCRL4, CD307d, CD307d antigen, FcR-like protein 4, Fc receptor-like 4, HIFGP2, IGFP2, IRTA1, Fc receptor homolog 4, Fc receptor-like protein 4, FCRH4, IFGP family protein 2, IFGP2 |
| Target Sequences: | NM_031282 NP_112572.1 Q96PJ5 |
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