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FCGR2 / CD32

CD32 is a surface receptor protein and part of a large population of B cell co-receptors, which act to modulate signaling. It has a low-affinity for IgG antibodies and down-regulates antibody production in the presence of IgG. This feedback loop acts to lower the production of IgG by B cells when there is a surplus in the body. Monoclonal antibodies can distinguish between CD32A and CD32B.

FCGR2 / CD32 Target Details

Target Name: FCGR2 / CD32

Publications (3)

1
C-reactive protein and annexin A5 bind to distinct sites of negatively charged phospholipids present in oxidized low-density lipoprotein. van Tits L, de Graaf J, Toenhake H, van Heerde W, Stalenhoef A. Arteriosclerosis, thrombosis, and vascular biology. 2005 25:717-22. [PubMed:15692104] Related Antibodies: LS-C41118.
2
Toll-like receptor 2 mediates the activation of human monocytes and endothelial cells by antiphospholipid antibodies. Satta N, Kruithof EK, Fickentscher C, Dunoyer-Geindre S, Boehlen F, Reber G, Burger D, de Moerloose P. Blood. 2011 117:5523-31. [PubMed:21330474] Related Antibodies: LS-C41118.
3
Factor H-IgG Chimeric Proteins as a Therapeutic Approach against the Gram-Positive Bacterial Pathogen Streptococcus pyogenes. Blom AM, Magda M, Kohl L, Shaughnessy J, Lambris JD, Ram S, Ermert D. Journal of immunology (Baltimore, Md. : 1950). 2017 December;199:3828-3839. [Full Text Article] [PubMed:29084837] [PMC:PMC5698128] Related Antibodies: LS-C187457.

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ELISA Kits (10)
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FCGR2 / CD32 (10)
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FCGR2 / CD32 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
46.875 - 3000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FCGR2 / CD32 ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
FCGR2 / CD32 ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
FCGR2 / CD32 ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
FCGR2 / CD32 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
FCGR2 / CD32 ELISA Kit
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Sandwich
96-Well Microplate
Human
46.875 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FCGR2 / CD32 ELISA Kit
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Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$923
FCGR2 / CD32 ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
FCGR2 / CD32 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.096 - 23.33 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$840
FCGR2 / CD32 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$1,150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).