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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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FcERI / Fc Epsilon RI
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
| Gene Name: | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| Family/Subfamily: | Immunoglobulin , not assigned-Immunoglobulin |
| Synonyms: | FCER1A, Alpha polypeptide, FCE1A, FcERI, Fc Epsilon RI, Fc epsilon RI alpha-chain, Fc-epsilon RI-alpha, IgE Fc receptor subunit alpha |
| Target Sequences: | NM_002001 NP_001992.1 P12319 |
Publications (1)
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