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FBXO4 / FBX4
F-box protein 4
FBXO4 / FBX4 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | F-box protein 4 |
| Family/Subfamily: | F-Box |
| Synonyms: | FBXO4, F-box protein 4, F-box protein Fbx4, FBX4, F-box only protein 4 |
| Target Sequences: | NM_012176 Q9UKT5 Q9UKT5 |
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