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FBXO38 is a large protein that contains an F-box domain and may participate in protein ubiquitination. The encoded protein is a transcriptional co-activator of Krueppel-like factor 7 (Klf7). A heterozygous mutation in this gene was found in individuals with autosomal dominant distal hereditary motor neuronopathy type IID. There is a pseudogene for this gene on chromosome 4. Alternative splicing results in multiple transcript variants.
Gene Name: | F-box Protein 38 |
Family/Subfamily: | F-Box |
Synonyms: | FBXO38, F-box only protein 38, Fbx38, F-box protein 38, MOKA, SP329 |
Target Sequences: | NM_030793 NP_110420.3 Q6PIJ6 |
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