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FBXO31
F-box protein 31
FBXO31 is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants.
| Gene Name: | F-box protein 31 |
| Family/Subfamily: | F-Box |
| Synonyms: | FBXO31, F-box protein 31, FBX14, FBXO14, F-box only protein 31, Fbx31, Pp2386 |
| Target Sequences: | NM_024735 NP_079011.3 Q5XUX0 |
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