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FBXO25
F-box protein 25
FBXO25 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
| Gene Name: | F-box protein 25 |
| Family/Subfamily: | F-Box |
| Synonyms: | FBXO25, F-box only protein 25, F-box protein 25, F-box protein Fbx25, FBX25 |
| Target Sequences: | AA749085 IPI00073356.1 Q8TCJ0 |
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