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FBXO21
F-box protein 21
FBXO21 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
| Gene Name: | F-box protein 21 |
| Family/Subfamily: | F-Box |
| Synonyms: | FBXO21, FBX21, F-box only protein 21, F-box protein 21, KIAA0875 |
| Target Sequences: | NM_033624 NP_296373.1 O94952 |
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