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Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC).
Gene Name: | F-box and leucine-rich repeat protein 22 |
Synonyms: | FBXL22 |
Target Sequences: | NP_976307.2 |
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