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FBXL12

F-box and leucine-rich repeat protein 12

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia.

Gene Name: F-box and leucine-rich repeat protein 12
Family/Subfamily: F-Box
Synonyms: FBXL12, Fbl12, F-box protein FBL12, F-box/LRR-repeat protein 12
Target Sequences: NM_017703 NP_060173.1 Q9NXK8

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Products
Antibodies (16)
Primary (16)
FBXL12 (16)
Human (16)
Mouse (6)
Rat (2)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (3)
Hamster (1)
Horse (1)
Monkey (4)
Pig (4)
Rabbit (3)
IHC (1)
IHC-P (2)
WB (14)
ELISA (6)
ICC (1)
IF (1)
Peptide-ELISA (1)
rabbit (15)
goat (1)
IgG (10)
polyclonal pc (16)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (8)
aa277-303 (7)
C-Terminus (4)
aa265-326 (1)
aa315-326 (1)
No (16)
FBXL12 Antibody - IHC of paraffin-embedded SW480 xenograft using FBXL12 antibody at 1:500 dilution.
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FBXL12 Rabbit anti-Human Polyclonal (aa265-326) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
FBXL12 Antibody - Immunofluorescence staining of FBXL12 in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human FBXL12 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
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FBXL12 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
Select
FBXL12 Rabbit anti-Human Polyclonal (aa277-303) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
FBXL12 Rabbit anti-Human Polyclonal (aa277-303) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
FBXL12 Rabbit anti-Human Polyclonal (aa277-303) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
FBXL12 Rabbit anti-Human Polyclonal (aa277-303) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
FBXL12 Rabbit anti-Human Polyclonal (aa277-303) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
FBXL12 Rabbit anti-Human Polyclonal (aa277-303) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
FBXL12 Antibody - Goat Anti-FBXL12 Antibody (4µg/ml) staining of paraffin embedded Human Lung. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
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FBXL12 Goat anti-Human Polyclonal (aa315-326) Antibody
Mouse, Dog, Rat, Hamster, Pig, Horse, Human, Monkey
IHC-P, Peptide-ELISA
Unconjugated
100 µg/$503
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FBXL12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
FBXL12 Antibody - FBXL12 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FBXL12 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
FBXL12 Antibody - FBXL12 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FBXL12 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Guinea pig, Pig, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
FBXL12 Antibody - FBXL12 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FBXL12 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Guinea pig, Pig, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
FBXL12 Antibody - FBXL12 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FBXL12 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Guinea pig, Pig, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
FBXL12 Antibody - Western blot analysis of extracts of various cell lines, using FBXL12 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
Select
FBXL12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
FBXL12 Antibody - FBXL12 Antibody western blot of SK-BR-3 cell line lysates (35 ug/lane). The FBXL12 antibody detected the FBXL12 protein (arrow).
Select
FBXL12 Rabbit anti-Human Polyclonal (aa277-303) Antibody
Human
WB
Unconjugated
400 µl/$393
Viewing 1-16 of 16 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).