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FBLIM1 / Migfilin
filamin binding LIM protein 1
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
| Gene Name: | filamin binding LIM protein 1 |
| Synonyms: | FBLIM1, CAL, CSX-associated LIM, FBLP1, Filamin-binding LIM protein 1, Filamin binding LIM protein 1, Filamin-binding LIM protein-1, MIG2-interacting protein, RP11-169K16.5, Migfilin, FBLP-1 |
| Target Sequences: | Q8WUP2 Q8WUP2 |
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