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FAU / Fub1

Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed

FAU is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome and displays antimicrobial activity. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin.

Gene Name: Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
Synonyms: FAU, 40S ribosomal protein S30, Asr1, Fub1, MNSFbeta, S30, FAU1, Fubi, Ribosomal protein S30, RPS30
Target Sequences: NM_001997 NP_001988.1 P35544

Publications (1)

1
High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel. Tomati V, Pesce E, Caci E, Sondo E, Scudieri P, Marini M, Amato F, Castaldo G, Ravazzolo R, Galietta LJV, Pedemonte N. The Journal of biological chemistry. 2018 January;293:1203-1217. [Full Text Article] [PubMed:29158263] [PMC:PMC5787799] Related Antibodies: LS-C97817.

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
FAU / Fub1 (6)
No (6)
GST (2)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
FAU / Fub1 Protein - Purified recombinant protein FAU was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
14.2 kDa
20 µg/$1,107
FAU / Fub1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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E. coli
GST
41.8 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
FAU / Fub1 Protein - 12.5% SDS-PAGE of human FAU stained with Coomassie Blue
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Wheat Germ Extract
GST
40.37 kDa
10 µg/$479; 25 µg/$670
FAU / Fub1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
14.2 kDa
100 µg/$494
FAU / Fub1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
14.2 kDa
20 µg/$150
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).