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FARSB encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified.
|Gene Name:||phenylalanyl-tRNA synthetase, beta subunit|
|Synonyms:||FARSB, FARSLB, FRSB, HSPC173, PheHB, PheRS|
|Target Sequences:||NM_005687 NP_005678.3 Q9NSD9|
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