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FAM175B / KIAA0157

family with sequence similarity 175, member B

Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. May act as a central scaffold protein that assembles the various components of the BRISC complex.

Gene Name:	family with sequence similarity 175, member B
Synonyms:	FAM175B, Abraxas brother protein 1, BRISC complex subunit Abro1, Abraxas brother 1, ABRO1, Em:AC068896.4, Protein FAM175B, KIAA0157
Target Sequences:	NM_032182 NP_115558.3 Q15018

Publications (1)

MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, Seidman MM, Greenberg RA. Genes & development. 2015 29:1955-68. (WB; Human) [Full Text Article] [PubMed:26338419] [PMC:PMC4579352] Related Antibodies: LS-C102632.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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