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Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor.
Gene Name: | multivesicular body subunit 12A |
Synonyms: | MVB12A, CFBP, ESCRT-I complex subunit MVB12A, FAM125A, Protein FAM125A |
Target Sequences: | NM_138401 NP_612410.1 Q96EY5 |
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