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Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
Gene Name: | Fanconi anemia core complex associated protein 24 |
Synonyms: | FAAP24, C19orf40 |
Target Sequences: | AA837644 |
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