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F2 / Prothrombin / Thrombin
coagulation factor II (thrombin)
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
| Gene Name: | coagulation factor II (thrombin) |
| Family/Subfamily: | Protease , Serine S1 |
| Synonyms: | F2, Prothrombin B-chain, Coagulation factor II, FACTOR II, Prothrombin, PT, RPRGL2, Serine protease, THPH1, Thrombin |
| Target Sequences: | NM_000506 NP_000497.1 P00734 |
Publications (3)
1
Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury. Radulovic M, Yoon H, Wu J, Mustafa K, Scarisbrick IA. Neurobiology of disease. 2016 93:226-42. (WB; Human)
[Full Text Article]
[PubMed:27145117]
Related Antibodies: LS-C118750.
2
Production and control of coagulation proteins for factor X activation in human endothelial cells and fibroblasts. Clay T Cohen, Nancy A Turner, Joel L Moake. Scientific reports. 2020 Feb;10:2005. [Full Text Article]
[PubMed:32029851]
[PMC:PMC7005260]
3
Maternal plasma proteomics in a rat model of pregnancy complications reveals immune and pro-coagulant gene pathway activation. Tino W Sanchez, Bo Li, Christine Molinaro, Carlos A Casiano, Denise L Bellinger, Eugenia Mata-Greenwood. American journal of reproductive immunology (New York, N.Y. : 1989). 2020 February;83:e13205. [Full Text Article]
[PubMed:31677200]
[PMC:PMC8553409]
☰ Filters
Products
Antibodies
(211)
Type
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(211)
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F2 / Prothrombin / Thrombin
(211)
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(102)
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(67)
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(82)
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(3)
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(3)
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(8)
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(6)
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(15)
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(11)
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(171)
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(61)
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(1)
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(6)
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(8)
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(1)
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(1)
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(4)
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(1)
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(1)
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rabbit
(120)
mouse
(47)
burro
(1)
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(1)
sheep
(42)
Product Group
IHCPlus
(8)
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IgG
(90)
IgG1
(3)
IgG1,k
(1)
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(6)
IgG2b,k
(8)
Clonality
monoclonal mc
(48)
polyclonal pc
(163)
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(1)
318
(1)
AHP-5013
(1)
Ca-Pro 20
(2)
OTI5B11
(2)
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(2)
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(13)
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(14)
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(26)
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(2)
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(13)
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(13)
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(22)
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(26)
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(14)
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(3)
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(83)
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aa44-200
(34)
aa324-617
(10)
aa325-618
(10)
aa201-323
(8)
aa201-324
(8)
aa44-198
(8)
aa130-179
(4)
aa44-622
(4)
Internal
(2)
250-330 aa, Internal
(1)
AP2, Cleaved-Arg327
(1)
Gly724
(1)
aa278-327
(1)
aa391-440
(1)
aa396-445
(1)
aa46-79
(1)
aa600-612
(1)
Publications
No
(210)
Yes
(1)
F2 / Prothrombin / Thrombin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
F2 / Prothrombin / Thrombin Sheep anti-Bovine Polyclonal Antibody
Bovine, Human
ELISA, IHC, IHC-P
Unconjugated
250 µg/$485
F2 / Prothrombin / Thrombin Mouse anti-Human Monoclonal (AHP-5013) Antibody
Human
ELISA, Inhb, WB
Unconjugated
100 µg/$397
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$427; 1 mg/$572; 10 mg/$3,208
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µg/$427; 1 mg/$572; 10 mg/$3,408
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µg/$427; 1 mg/$572; 10 mg/$3,633
F2 / Prothrombin / Thrombin Sheep anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IE
HRP Conjugated
200 µg/$657
F2 / Prothrombin / Thrombin Sheep anti-Bovine Polyclonal (HRP) Antibody
Bovine
ELISA, IE
HRP Conjugated
200 µg/$665
F2 / Prothrombin / Thrombin Sheep anti-Human Polyclonal Antibody
Human
Unconjugated
10 mg/$515
F2 / Prothrombin / Thrombin Sheep anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
200 µg/$657
F2 / Prothrombin / Thrombin Sheep anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.5 mg/$485
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal (aa396-445) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
F2 / Prothrombin / Thrombin Sheep anti-Bovine Polyclonal Antibody
Bovine
ELISA
Unconjugated
1 mg/$459
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal (Gly724) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
F2 / Prothrombin / Thrombin Rabbit anti-Rat Polyclonal (aa130-179) Antibody
Rat
WB
Unconjugated
100 µl/$424
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
F2 / Prothrombin / Thrombin Sheep anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
1 ml/$424
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$427; 1 ml/$572; 10 ml/$3,497
F2 / Prothrombin / Thrombin Sheep anti-Human Polyclonal Antibody
Human
ELISA, IE, RIA
Unconjugated
500 µg/$732
F2 / Prothrombin / Thrombin Sheep anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
1 mg/$389
F2 / Prothrombin / Thrombin Sheep anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
1 mg/$366; 5 mg/$553
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal (aa278-327) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
F2 / Prothrombin / Thrombin Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$365; 200 µl/$431; 500 µl/$678; 1 ml/$838; 2 ml/$1,082; 5 ml/$1,925
F2 / Prothrombin / Thrombin Rabbit anti-Mouse Monoclonal (Preservative Free) (318) Antibody
Mouse
WB
Unconjugated, Preservative Free
100 µl/$412
F2 / Prothrombin / Thrombin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 26-50
of 211
product results
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