F13B / TGase

coagulation factor XIII, B polypeptide

F13B / TGase is coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.

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Proteins (4)

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Over-Expression Lysate (2)

Recombinant (2)

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F13B / TGase (4)

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His (2)

Myc-DDK (Flag) (2)

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Human (2)

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E. coli (1)

HEK 293 Cells (1)

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Low endotoxin level (1)

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Human F13B / TGase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87854

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

75.51 kDa

Price:

20 µg/$215

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F13B / TGase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118251

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

75.51 kDa

Price:

100 µg/$710

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Mouse F13B / TGase Protein (Recombinant His) (aa21-208) - LS-G24383

Source:

E. coli

Tag:

His

Molecular Weight:

25.0 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human F13B / TGase Protein (Recombinant His) (Met1-Thr661) - LS-G98574

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

74.5 kDa

Price:

50 µg/$843

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