F13B / TGase

coagulation factor XIII, B polypeptide

F13B / TGase is coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.

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Products

ELISA Kits (15)

Type

Competitive EIA (2)

Sandwich (12)

Sandwich CLIA (1)

Target

F13B / TGase (15)

Reactivity

Human (5)

Mouse (6)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (12)

Publications

No (15)

Sample Type

Plasma (11)

Serum (9)

Tissue Homogenates (3)

Urine (1)

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Human F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F33961

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F21800

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Chicken F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F42477

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Monkey F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F42478

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Porcine F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F42479

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F42480

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Mouse F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F66937

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F66528

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse F13B / TGase (CLIA) ELISA Kit - LS-F30596

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

0.625 - 40 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Mouse F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F21837

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse F13B / TGase (Competitive EIA) ELISA Kit - LS-F28335

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

10 - 250 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Mouse F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F56475

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F51859

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$958

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Mouse F13B / TGase (Sandwich ELISA) ELISA Kit - LS-F5842

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

3.13 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$818

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Human F13B / TGase (Competitive EIA) ELISA Kit - LS-F9966

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.23 - 100 µg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$798

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