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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EYA3

eyes absent homolog 3 (Drosophila)

Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1, and seems to coactivate SIX2, SIX4 and SIX5. The repression of precursor cell proliferation in myoblasts by SIX1 is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex and seems to be dependent on EYA3 phosphatase activity (By similarity). May be involved in development of the eye.

Gene Name: eyes absent homolog 3 (Drosophila)
Synonyms: EYA3, Eyes absent 3, Eyes absent homolog 3
Target Sequences: NM_001990 NP_001981.2 Q99504

Filtered By: None
Target
EYA3 (21)
Reactivity
Human (21)
Mouse (8)
Rat (7)
Bat (4)
Bovine (6)
Chimpanzee (9)
Dog (6)
Gibbon (9)
Guinea pig (10)
Horse (6)
Monkey (4)
Orangutan (6)
Rabbit (10)
Sheep (6)
Application
IHC (12)
IHC-P (6)
WB (19)
ELISA (3)
IF (5)
IP (3)
Host
rabbit (21)
Isotype
IgG (12)
Clonality
polyclonal pc (21)
Format
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (12)
Epitope
N-Terminus (4)
aa237-286 (4)
aa277-326 (4)
aa1-30 (2)
aa30-60 (1)
Publications
No (21)
Showing 1-21 of 21 results

EYA3 Antibody LS-C665461
Rabbit Polyclonal (IgG) to Human EYA3
Human
ELISA IF IHC IP WB
Unconjugated
100µg  $335.00

EYA3 Antibody LS-C682114
Rabbit Polyclonal (IgG) to Human EYA3
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue at dilution 1:100

EYA3 Antibody LS-C675731
Rabbit Polyclonal (IgG) to Human EYA3
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue at dilution 1:100

EYA3 Antibody (aa1-30) LS-C289412
Rabbit Polyclonal (IgG) to Human EYA3
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Horse, Human
IF IHC IHC-P IP WB
Unconjugated
100µl 0.2mg/ml  $395.00
Detection of Human EYA3 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-EYA3 used at a dilution of 1:200 (1 Detection: DAB.
Detection of Human EYA3 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-EYA3 used at a dilution of 1:200 (1 Detection: DAB.

EYA3 Antibody (aa30-60) LS-C289413
Rabbit Polyclonal (IgG) to Human EYA3
Human
IF IHC IHC-P IP
Unconjugated
100µl 1mg/ml  $395.00

EYA3 Antibody LS-C409440
Rabbit Polyclonal (IgG) to Human EYA3
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $255.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded rat kidney tissue.
Immunohistochemistry of paraffin-embedded human kidney tissue.
Immunohistochemistry of paraffin-embedded rat kidney tissue.
Immunohistochemistry of paraffin-embedded human kidney tissue.

EYA3 Antibody (aa1-30) LS-C286942
Rabbit Polyclonal (IgG) to Human EYA3
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Horse, Human
IF IHC IHC-P
Unconjugated
100µl  $415.00
Detection of Human EYA3 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-EYA3 used at a dilution of 1:250.
Detection of Human EYA3 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-EYA3 used at a dilution of 1:250.

EYA3 Antibody LS-C482914
Rabbit Polyclonal to Human EYA3
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Immunohistochemical analysis of EYA3 staining in rat kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of EYA3 expression in HeLa (A); HT29 (B); mouse eye (C); mouse testis (D); rat brain (E); rat liver (F) whole cell lysates.
Immunohistochemical analysis of EYA3 staining in rat kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of EYA3 expression in HeLa (A); HT29 (B); mouse eye (C); mouse testis (D); rat brain (E); rat liver (F) whole cell lysates.

EYA3 Antibody LS-C750031
Rabbit Polyclonal (IgG) to Human EYA3
Rat, Human
IF WB
Unconjugated
50µl  $235.00
Immunofluorescence analysis of U2OS cells using EYA3 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using EYA3 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

EYA3 Antibody (aa277-326) LS-C29714
Rabbit Polyclonal (IgG) to Human EYA3
Human, Monkey
IHC WB
Unconjugated
50µg  $365.00
Human Skeletal Muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Skeletal Muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (aa277-326, HRP) LS-C427682
Rabbit Polyclonal (IgG) to Human EYA3
Human, Monkey, Chimpanzee, Gibbon
IHC WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Human Skeletal Muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Skeletal Muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (aa277-326, Biotin) LS-C427680
Rabbit Polyclonal (IgG) to Human EYA3
Human, Monkey, Chimpanzee, Gibbon
IHC WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Human Skeletal Muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Skeletal Muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (aa277-326, FITC) LS-C427681
Rabbit Polyclonal (IgG) to Human EYA3
Human, Monkey, Chimpanzee, Gibbon
IHC WB
FITC Conjugated
100µl 1mg/ml  $385.00
Human Skeletal Muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Skeletal Muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (N-Terminus) LS-C201253
Rabbit Polyclonal to Human EYA3
Rabbit, Dog, Guinea pig, Sheep, Bovine, Horse, Bat, Human
WB
Unconjugated
50µg  $365.00
Western blot of Human Fetal Spleen. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Fetal Spleen. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (N-Terminus, HRP) LS-C427679
Rabbit Polyclonal to Human EYA3
Rabbit, Dog, Guinea pig, Sheep, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Western blot of Human Fetal Spleen. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Fetal Spleen. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (N-Terminus, Biotin) LS-C427677
Rabbit Polyclonal to Human EYA3
Rabbit, Dog, Guinea pig, Sheep, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Western blot of Human Fetal Spleen. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Fetal Spleen. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (N-Terminus, FITC) LS-C427678
Rabbit Polyclonal to Human EYA3
Rabbit, Dog, Guinea pig, Sheep, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
Western blot of Human Fetal Spleen. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Fetal Spleen. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (aa237-286) LS-C187218
Rabbit Polyclonal to Human EYA3
Rabbit, Mouse, Guinea pig, Rat, Human
WB
Unconjugated
50µg  $365.00
Western blot of Human Thymus Tumor. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Thymus Tumor. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (aa237-286, HRP) LS-C464083
Rabbit Polyclonal to Human EYA3
Rabbit, Mouse, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Western blot of Human Thymus Tumor. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Thymus Tumor. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (aa237-286, Biotin) LS-C464375
Rabbit Polyclonal to Human EYA3
Rabbit, Mouse, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Western blot of Human Thymus Tumor. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Thymus Tumor. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EYA3 Antibody (aa237-286, FITC) LS-C464082
Rabbit Polyclonal to Human EYA3
Rabbit, Mouse, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human
WB
FITC Conjugated
100µl 1mg/ml  $385.00
Western blot of Human Thymus Tumor. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Thymus Tumor. EYA3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-21 of 21 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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