ETHE1

ethylmalonic encephalopathy 1

Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H2S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H2S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (PubMed:12398897).

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Products

Antibodies (18)

Proteins (7)

Type

Over-Expression Lysate (2)

Primary (18)

Recombinant (5)

Target

ETHE1 (25)

Reactivity

Human (18)

Mouse (12)

Rat (5)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Application

IHC (9)

IHC-P (5)

WB (17)

Flo (1)

ELISA (8)

IF (1)

IP (2)

Host

rabbit (17)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (8)

Clonality

polyclonal pc (18)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (12)

Epitope

aa92-141 (4)

aa103-130 (1)

aa180-209 (1)

Publications

No (25)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-SUMO (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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ETHE1 Antibody (aa103-130) LS-C98379

Antibody:

ETHE1 Rabbit anti-Human Polyclonal (aa103-130) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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IHC-plus™ ETHE1 Antibody (aa180-209) LS-B10538

(4.0) Rating

Antibody:

ETHE1 Rabbit anti-Human Polyclonal (aa180-209) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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ETHE1 Antibody LS-C486298

Antibody:

ETHE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

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ETHE1 Antibody LS-C307437

Antibody:

ETHE1 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$705

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Human ETHE1 Protein (Recombinant His) - LS-G1601

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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ETHE1 Antibody LS-C375668

Antibody:

ETHE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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ETHE1 Antibody (HRP) LS-C375666

Antibody:

ETHE1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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ETHE1 Antibody (Biotin) LS-C375671

Antibody:

ETHE1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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ETHE1 Antibody (FITC) LS-C375664

Antibody:

ETHE1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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ETHE1 Antibody LS-C401646

Antibody:

ETHE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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ETHE1 Antibody LS-C486296

Antibody:

ETHE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

ETHE1 Antibody LS-C486297

Antibody:

ETHE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

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ETHE1 Antibody LS-C766448

Antibody:

ETHE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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ETHE1 Antibody (aa92-141) LS-C117062

Antibody:

ETHE1 Rabbit anti-Human Polyclonal (aa92-141) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ETHE1 Antibody (aa92-141, HRP) LS-C459512

Antibody:

ETHE1 Rabbit anti-Human Polyclonal (aa92-141) (HRP) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

ETHE1 Antibody (aa92-141, Biotin) LS-C459510

Antibody:

ETHE1 Rabbit anti-Human Polyclonal (aa92-141) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

ETHE1 Antibody (aa92-141, FITC) LS-C459511

Antibody:

ETHE1 Rabbit anti-Human Polyclonal (aa92-141) (FITC) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ETHE1 Antibody LS-C668504

Antibody:

ETHE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

ETHE1 Antibody LS-C496854

Antibody:

ETHE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

Human ETHE1 Protein (Recombinant GST, N-terminus) (aa155-254) - LS-G62010

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ETHE1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85854

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.7 kDa

Price:

20 µg/$150

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Human ETHE1 Protein (Recombinant His-SUMO) (aa8-254) - LS-G20715

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

43.08 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human ETHE1 Protein (Recombinant GST) (Full Length) - LS-G32855

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

54.3 kDa

Price:

10 µg/$479; 25 µg/$670

Select

ETHE1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101190

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.7 kDa

Price:

100 µg/$494

Select

Human ETHE1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69921

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.7 kDa

Price:

20 µg/$1,107

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