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ESRP2 / RBM35B

epithelial splicing regulatory protein 2

mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Gene Name: epithelial splicing regulatory protein 2
Synonyms: ESRP2, RBM35B, RNA binding motif protein 35A, RNA-binding protein 35B, RNA-binding motif protein 35B, RNA binding motif protein 35B
Target Sequences: NM_024939 NP_079215.2 Q9H6T0

Publications (1)

1
An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition. Warzecha CC, Jiang P, Amirikian K, Dittmar KA, Lu H, Shen S, Guo W, Xing Y, Carstens RP. The EMBO journal. 2010 29:3286-300. [PubMed:20711167] [PMC:PMC2957203] Related Antibodies: LS-C153834.

☰ Filters
Antibodies (27)
Proteins (4)
Over-Expression Lysate (2)
Primary (27)
Recombinant (2)
ESRP2 / RBM35B (31)
Human (22)
Mouse (21)
Rat (10)
Bat (3)
Bovine (6)
Chimpanzee (3)
Dog (3)
Gibbon (6)
Guinea pig (6)
Horse (3)
Monkey (9)
Pig (3)
Rabbit (9)
Xenopus (3)
IHC (3)
IHC-P (1)
WB (22)
ELISA (6)
IF (2)
Peptide-ELISA (1)
rabbit (25)
mouse (2)
IgG (16)
IgG2a,k (2)
monoclonal mc (2)
polyclonal pc (25)
22C5.H7.A6 (2)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
Unconjugated (12)
N-Terminus (4)
aa36-85 (4)
aa600-649 (4)
aa61-110 (4)
No (30)
Yes (1)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
ESRP2 / RBM35B Antibody - Anti-ESRP2 by western blot shows detection of ESRP2 in transfected 293T cell extracts (lane 2). Lanes ug and 1 contain 5 ug GFP-transfected- and ESRP1-transfected 293T cell lysates, respectively. Briefly, each lane contains approximately 5 ug of lysate. Primary antibody was used at a 1:1000 dilution (PBS-T plus milk) and reacted for O/N at 4C. The membrane was washed and reacted with a 1:10000 dilution of an anti-mouse ECL antibody for 1hr at room temperature. The bands shown are full length FLAG-ESRP2 (~80kDa) and a slightly lower band that is specific to ESRP2. Molecular weight estimation was made by comparison to prestained MW markers.
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ESRP2 / RBM35B Mouse anti-Mouse Monoclonal (22C5.H7.A6) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$574
ESRP2 / RBM35B Antibody - Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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ESRP2 / RBM35B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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ESRP2 / RBM35B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
ESRP2 / RBM35B Antibody - Immunohistochemistry of RBM35B in human lung tissue with RBM35B antibody at 5 µg/mL.
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ESRP2 / RBM35B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
ESRP2 / RBM35B Antibody - Anti-ESRP2 by western blot shows detection of ESRP2 in transfected 293T cell extracts (lane 2). Lanes G and 1 contain 5ug GFP-transfected- and ESRP1-transfected 293T cell lysates, respectively. Briefly, each lane contains approximately 5 µg of lysate. Primary antibody was used at a 1:1000 dilution (PBS-T plus milk) and reacted for O/N at 4C. The membrane was washed and reacted with a 1:10,000 dilution of an anti-mouse ECL antibody for 1hr at room temperature. The bands shown are full length FLAG-ESRP2 (~80kDa) and a slightly lower band that is specific to ESRP2. Molecular weight estimation was made by comparison to prestained MW markers.
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ESRP2 / RBM35B Mouse anti-Mouse Monoclonal (22C5.H7.A6) Antibody
Mouse
ELISA, WB
Unconjugated
25 µl/$304
ESRP2 / RBM35B Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using ESRP2 Polyclonal Antibody at dilution of 1:95(×200)
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ESRP2 / RBM35B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ESRP2 / RBM35B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
ESRP2 / RBM35B Antibody - Western blot analysis of RBM35B expression in HeLa cells lysate. The lane on the left is treated with the antigen-specific peptide.
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ESRP2 / RBM35B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ESRP2 / RBM35B Antibody - NIH 3T3 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (aa61-110) Antibody
Mouse
WB
Unconjugated
100 µl/$397
ESRP2 / RBM35B Antibody - NIH 3T3 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (aa61-110) (HRP) Antibody
Rabbit, Mouse, Dog, Rat, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$442
ESRP2 / RBM35B Antibody - NIH 3T3 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (aa61-110) (Biotin) Antibody
Rabbit, Mouse, Dog, Rat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$442
ESRP2 / RBM35B Antibody - NIH 3T3 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (aa61-110) (FITC) Antibody
Rabbit, Mouse, Dog, Rat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$442
ESRP2 / RBM35B Antibody - ESRP2 / RBM35B antibody Western blot of Mouse Liver lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (aa600-649) Antibody
Mouse
WB
Unconjugated
100 µl/$424
ESRP2 / RBM35B Antibody - ESRP2 / RBM35B antibody Western blot of Mouse Liver lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (aa600-649) (HRP) Antibody
Xenopus, Bat, Rat, Pig, Horse, Rabbit, Mouse, Guinea pig, Bovine, Human, Monkey, Gibbon
WB
HRP Conjugated
100 µl/$469
ESRP2 / RBM35B Antibody - ESRP2 / RBM35B antibody Western blot of Mouse Liver lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (aa600-649) (Biotin) Antibody
Xenopus, Bat, Rat, Pig, Horse, Rabbit, Mouse, Guinea pig, Bovine, Human, Monkey, Gibbon
WB
Biotin Conjugated
100 µl/$469
ESRP2 / RBM35B Antibody - ESRP2 / RBM35B antibody Western blot of Mouse Liver lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (aa600-649) (FITC) Antibody
Xenopus, Bat, Rat, Pig, Horse, Rabbit, Mouse, Guinea pig, Bovine, Human, Monkey, Gibbon
WB
FITC Conjugated
100 µl/$469
ESRP2 / RBM35B Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
WB
Unconjugated
100 µl/$424
ESRP2 / RBM35B Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$469
ESRP2 / RBM35B Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$469
ESRP2 / RBM35B Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Mouse Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Human
WB
FITC Conjugated
100 µl/$469
ESRP2 / RBM35B Antibody - ESRP2 / RBM35B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
WB
Unconjugated
100 µl/$424
ESRP2 / RBM35B Antibody - ESRP2 / RBM35B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ESRP2 / RBM35B Antibody - ESRP2 / RBM35B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ESRP2 / RBM35B Antibody - ESRP2 / RBM35B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ESRP2 / RBM35B Rabbit anti-Human Polyclonal (aa36-85) (FITC) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Select
ESRP2 / RBM35B Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µg/$341
Viewing 1-25 of 31 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).