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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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ESR2 / ER Beta

estrogen receptor 2 (ER beta)

Estrogen receptor beta (ER beta), a NR3 Steroid Receptor, has been shown to have physiological functions in the central nervous system, cardiovascular system, immune system, urogenital tract, gastrointestinal tract, and in bone, kidney, and lung. Mice lacking the gene for ER beta show defective ovary development, reduced fertility, abnormal bladder and prostate development, and impaired vascular system functions that lead to hypertension in aging. ER beta is phosphorylated upon ligand activation and binds to target DNA as a homodimer. At least eight alternatively spliced isoforms of ER beta have been documented, many of which show tissue-specific expression patterns. A novel and functionally distinct isoform of human ER beta (ER beta548), which includes an extended amino-terminal domain has been identified recently by Wilkinson et al. 2002. ER beta has been suggested to affect carcinogenesis in smooth muscle, urogenital tract, breast, and colonic tissues.

Gene Name: estrogen receptor 2 (ER beta)
Family/Subfamily: NHR , NR3 Steroid receptor
Synonyms: ESR2, ESTRB, ER Beta, ERbeta, ER-BETA, ESR-BETA, ESRB, Estrogen receptor 2 (ER beta), NR3A2, Estrogen receptor beta, Estrogen receptor beta 4
Target Sequences: NM_001437 NP_001428.1 Q92731

Viewing 1-25 of 177 items
ESR2 / ER Beta Antibody - Anti-ER-Beta antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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(1) Publication(s)
Rabbit Polyclonal to Human ESR2 / ER Beta
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Human
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $485.00
ESR2 / ER Beta Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human ESR2 / ER Beta
Human
IHC, IHC-P
Unconjugated
50µg   $425.00
ESR2 / ER Beta Antibody - Immunofluorescence analysis of HeLa cells, using Estrogen Receptor-beta Antibody. The picture on the right is blocked with the synthesized peptide.
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Rabbit Polyclonal (IgG) to Human ESR2 / ER Beta
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
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Rabbit Polyclonal to Mouse ESR2 / ER Beta
Mouse
IHC, IHC-Fr, IHC-P, WB
Unconjugated
50µg   $725.00
ESR2 / ER Beta Antibody - Estrogen Receptor beta antibody ERb455 immunohistochemistry breast cancer.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone ERb455] (IgG2a) to Human ESR2 / ER Beta
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
ESR2 / ER Beta Antibody - Estrogen Receptor beta antibody ERb455 immunohistochemistry breast cancer.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone ERb455] (IgG2a) to Human ESR2 / ER Beta
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Ready-to-Use
7ml   $465.00
ESR2 / ER Beta Antibody - Estrogen Receptor beta antibody ERb455 immunohistochemistry breast cancer.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone ERb455] (IgG2a) to Human ESR2 / ER Beta
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00
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Rabbit Polyclonal to Human ESR2 / ER Beta
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl   $385.00
ESR2 / ER Beta Antibody - Formalin-fixed, paraffin-embedded human bladder carcinoma stained with Estrogen Receptor beta antibody (ESR2/686).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone ESR2/686] (IgG2a) to Human ESR2 / ER Beta
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
ESR2 / ER Beta Antibody - Formalin-fixed, paraffin-embedded human bladder carcinoma stained with Estrogen Receptor beta antibody (ESR2/686).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone ESR2/686] (IgG2a) to Human ESR2 / ER Beta
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7ml   $465.00
ESR2 / ER Beta Antibody - Formalin-fixed, paraffin-embedded human bladder carcinoma stained with Estrogen Receptor beta antibody (ESR2/686).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone ESR2/686] (IgG2a) to Human ESR2 / ER Beta
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00
ESR2 / ER Beta Antibody - IHC testing of breast cancer stained with Estrogen Receptor beta antibody (ERb455).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone NR3Gb-1] (IgG2a) to Human ESR2 / ER Beta
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
ESR2 / ER Beta Antibody - IHC testing of breast cancer stained with Estrogen Receptor beta antibody (ERb455).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone NR3Gb-1] (IgG2a) to Human ESR2 / ER Beta
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7ml   $465.00
ESR2 / ER Beta Antibody - IHC testing of breast cancer stained with Estrogen Receptor beta antibody (ERb455).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone NR3Gb-1] (IgG2a) to Human ESR2 / ER Beta
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00
Select
Rabbit Polyclonal to Mouse ESR2 / ER Beta
Mouse, Rat, Bat, Human, Monkey
GS, ICC, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50µg   $755.00
ESR2 / ER Beta Antibody
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Rabbit Polyclonal (IgG) to Human ESR2 / ER Beta
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
ESR2 / ER Beta Antibody - ESR2 / ER-Beta antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human ESR2 / ER Beta
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
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Chicken Polyclonal to Human ESR2 / ER Beta
Mouse, Rat, Human
WB
Unconjugated
100µg   100µl   1mg/ml   $365.00
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Rabbit Polyclonal (IgG) to Human ESR2 / ER Beta
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human ESR2 / ER Beta
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ESR2 / ER Beta
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human ESR2 / ER Beta
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human ESR2 / ER Beta
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ESR2 / ER Beta
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl   $740.00
ESR2 / ER Beta Antibody
Select
Rabbit Polyclonal (IgG) to Human ESR2 / ER Beta
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00

Viewing 1-25 of 177 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).