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Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3.
Gene Name: | establishment of sister chromatid cohesion N-acetyltransferase 2 |
Synonyms: | ESCO2, ECO1 homolog 2, EFO2, Roberts syndrome, N-acetyltransferase ESCO2, RBS |
Target Sequences: | NM_001017420 NP_001017420.1 Q56NI9 |
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