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Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.
Gene Name: | establishment of sister chromatid cohesion N-acetyltransferase 1 |
Synonyms: | ESCO1, CTF, CTF7 homolog 1, ECO1, EFO1, EFO1p, ECO1 homolog 1, HEFO1, KIAA1911, N-acetyltransferase ESCO1, ESO1, ESO1 homolog 1 |
Target Sequences: | Q5FWF5 Q5FWF5 |
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