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ERVFRD-1 / HERV-FRD

Endogenous Retrovirus group FRD, member 1

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Gene Name: Endogenous Retrovirus group FRD, member 1
Synonyms: ERVFRD-1, GLLL6191, Envelope polyprotein, EnvFRD, ERVFRDE1, HERV-FRD, UNQ6191, Syncytin-2, HERV-W/FRD, Syncytin 2
Target Sequences: R98276 NP_997465.1 P60508

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Proteins (1)
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ERVFRD-1 / HERV-FRD (1)
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Retroviridae (1)
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Wheat Germ Extract (1)
Purified (1)
ERVFRD-1 / HERV-FRD Protein - 12.5% SDS-PAGE of human ERVFRD-1 stained with Coomassie Blue
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Wheat Germ Extract
GST
85.9 kDa
2 µg/$439
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).