ERO1A / ERO1L

ERO1-like (S. cerevisiae)

Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

ERO1A / ERO1L (8)

Publications

No (8)

Tag

6His, C-terminus (2)

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (2)

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Human ERO1A / ERO1L Protein (Recombinant His) - LS-G2884

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human ERO1A / ERO1L Protein (Recombinant GST) (Full Length) - LS-G33503

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

80.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ERO1A / ERO1L Protein (Recombinant GST, N-terminus) (aa90-178) - LS-G62345

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ERO1A / ERO1L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90001

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.2 kDa

Price:

20 µg/$150

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ERO1A / ERO1L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113849

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.2 kDa

Price:

100 µg/$494

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Human ERO1A / ERO1L Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71530

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.2 kDa

Price:

20 µg/$1,107

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Human ERO1A / ERO1L Protein (Recombinant 6His, C-terminus) (Glu24-His468) - LS-G140153

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

53.0 kDa

Price:

10 µg/$317; 50 µg/$524

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Human ERO1A / ERO1L Protein (Recombinant 6His, C-terminus) (Glu24-His468) - LS-G39308

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

53kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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