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ERN2

endoplasmic reticulum to nucleus signaling 2

The endoribonuclease IRE2/ERN2 encodes the ER-to-nucleus signaling 2 protein, a human homolog of the yeast Ire1 gene product. In S. cerevisiae, as well as in human, this ER transmembrane IRE serine/threonine protein kinase monitors the status of unfolded proteins inside the ER lumen in response to stress.

Gene Name: endoplasmic reticulum to nucleus signaling 2
Family/Subfamily: Protein Kinase , IRE
Synonyms: ERN2, ER to nucleus signalling 2, HIRE2p, Inositol-requiring protein 2, IRE1-BETA, Inositol-requiring 1 beta, IRE1 beta, IRE2, IRE1b
Target Sequences: AB047079 BAB21297.1 Q76MJ5

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Proteins (2)
Over-Expression Lysate (2)
ERN2 (2)
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ERN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
107 kDa
20 µg/$215
ERN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
107 kDa
100 µg/$710
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).