ERI1 / HEXO

exoribonuclease 1

RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

ERI1 / HEXO (7)

Publications

No (7)

Tag

GST (1)

His-T7, N-terminus (2)

Myc-DDK (Flag) (4)

Species

Human (5)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human ERI1 / HEXO Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68695

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.9 kDa

Price:

20 µg/$1,107

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Human ERI1 / HEXO Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68696

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.3 kDa

Price:

20 µg/$1,107

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Human ERI1 / HEXO Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82816

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.9 kDa

Price:

20 µg/$150

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Human ERI1 / HEXO Protein (Recombinant GST) (Full Length) - LS-G35980

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

66.5 kDa

Price:

10 µg/$479; 25 µg/$670

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ERI1 / HEXO Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105781

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.9 kDa

Price:

100 µg/$494

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Human ERI1 / HEXO Protein (Recombinant His-T7, N-terminus) (Glu2-Lys249) - LS-G133332

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

43.6kDa

Price:

10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Mouse ERI1 / HEXO Protein (Recombinant His-T7, N-terminus) (Met1-Lys345) - LS-G133472

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

43.2kDa

Price:

10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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