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ERCC6 / CSB

excision repair cross-complementing rodent repair deficiency, complementation group 6

Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.

Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms: ERCC6, ARMD5, Cockayne syndrome B protein, Cockayne syndrome protein CSB, COFS, CSB, Rad26 homolog, ATP-dependent helicase ERCC6, CKN2, COFS1, RAD26, UVSS1
Target Sequences: NM_000124 NP_000115.1 Q03468

☰ Filters
Antibodies (22)
Proteins (5)
Over-Expression Lysate (2)
Primary (22)
Recombinant (3)
ERCC6 / CSB (27)
Human (22)
Mouse (5)
Rat (5)
Bat (1)
Bovine (1)
Chicken (1)
Chimpanzee (3)
Gibbon (3)
Monkey (4)
Orangutan (3)
Pig (1)
Rabbit (1)
IHC (6)
IHC-P (2)
WB (16)
DB (2)
ELISA (5)
IP (2)
Peptide-ELISA (3)
rabbit (17)
mouse (4)
goat (1)
Product Group
IHCPlus (1)
IgG (10)
IgG2a (1)
IgG2b (3)
monoclonal mc (4)
polyclonal pc (18)
553C5a (2)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (19)
aa784-833 (4)
110-190 aa, N-terminal (1)
N-Terminus (1)
aa1-50 (1)
aa1161-1211 (1)
aa141-190 (1)
aa242-261 (1)
aa346-766 (1)
aa717-731 (1)
No (27)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Select
ERCC6 / CSB Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
50 µg/$558
ERCC6 / CSB Antibody - Immunohistochemical analysis of ERCC6 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
Select
ERCC6 / CSB Mouse anti-Human Monoclonal (aa242-261) Antibody
Human
ELISA, WB
Unconjugated
150 µg/$842
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$341
ERCC6 / CSB Antibody - Anti-CSB / ERCC6 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal (aa346-766) Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$460
ERCC6 / CSB Antibody - 1:100 staining mouse spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal (110-190 aa, N-terminal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ERCC6 / CSB Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ERCC6 antibody.
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$357
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal (aa141-190) Antibody
Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
ERCC6 / CSB Antibody - Western blot analysis of immunized recombinant protein, using anti-ERCC6 monoclonal antibody.
Select
ERCC6 / CSB Mouse anti-Human Monoclonal (553C5a) Antibody
Human
DB, WB
Unconjugated
100 µg/$486
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ERCC6 / CSB Antibody - ERCC6 antibody (0.3 ug/ml) staining of HeLa nuclear lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Select
ERCC6 / CSB Goat anti-Human Polyclonal (aa717-731) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Bat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
Select
ERCC6 / CSB Mouse anti-Human Monoclonal (553C5a) Antibody
Human
DB
Unconjugated
100 µg/$965
ERCC6 / CSB Antibody - Western blot of Human HepG2. ERCC6 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal (aa784-833) Antibody
Human
WB
Unconjugated
100 µl/$424
ERCC6 / CSB Antibody - Western blot of Human HepG2. ERCC6 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal (aa784-833) (HRP) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
ERCC6 / CSB Antibody - Western blot of Human HepG2. ERCC6 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal (aa784-833) (Biotin) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
ERCC6 / CSB Antibody - Western blot of Human HepG2. ERCC6 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal (aa784-833) (FITC) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
ERCC6 / CSB Antibody - Western blot - Anti-CSB Picoband Antibody
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
ERCC6 / CSB Antibody - Western blot of ERCC6 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: H9C2 whole cell lysate. Lane 4: HELA whole cell ly.
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
ERCC6 / CSB Antibody - Western blot testing of 1) rat liver and 2) COLO320 lysate with CSB antibody at 0.5ug/ml. Predicted/observed molecular weight: ~168 kDa.
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
100 µg/$575
Select
ERCC6 / CSB Rabbit anti-Human Polyclonal (aa1161-1211) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
ERCC6 / CSB Protein - Purified recombinant protein ERCC6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
168.2 kDa
20 µg/$1,107
ERCC6 / CSB Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ERCC6 / CSB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
168.2 kDa
20 µg/$215
Viewing 1-25 of 27 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).