ERCC5 / XPG

excision repair cross-complementing rodent repair deficiency, complementation group 5

ERCC5 / XPG is a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ERCC5 / XPG (5)

Publications

No (5)

Tag

6His, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Purification

Purified (1)

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ERCC5 / XPG Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123383

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

133.1 kDa

Price:

100 µg/$494

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Human ERCC5 / XPG Protein (Recombinant 6His, N-terminus) (aa947-1186) - LS-G56241

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human ERCC5 / XPG Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69717

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

133.1 kDa

Price:

20 µg/$1,107

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Human ERCC5 / XPG Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85399

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

133.1 kDa

Price:

20 µg/$150

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Human ERCC5 / XPG Protein (Recombinant His-T7) (aa778-986) - LS-G14379

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.8 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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