ERCC5 / XPG

excision repair cross-complementing rodent repair deficiency, complementation group 5

ERCC5 / XPG is a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.

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ELISA Kits (5)

Type

Cell-Based (1)

Custom (2)

Sandwich (1)

Sandwich CLIA (1)

Target

ERCC5 / XPG (5)

Reactivity

Human (4)

Mouse (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (4)

Publications

No (5)

Sample Type

Adherent Cell Cultures (1)

Cell Lysates (1)

Tissue Homogenates (2)

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Mouse ERCC5 / XPG (Custom ELISA) ELISA Kit - LS-F15994

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human ERCC5 / XPG (Custom ELISA) ELISA Kit - LS-F15993

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human ERCC5 / XPG (Cell-Based ELISA) ELISA Kit - LS-F3082

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Human ERCC5 / XPG (CLIA) ELISA Kit - LS-F26564

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

13.72 - 10000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Tissue Homogenates

Price:

1 Plate/$968

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Human ERCC5 / XPG (Sandwich ELISA) ELISA Kit - LS-F5039

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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