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ERCC4 / XPF

excision repair cross-complementing rodent repair deficiency, complementation group 4

Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link.

Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 4
Synonyms: ERCC4, ERCC11, DNA repair endonuclease XPF, XPF
Target Sequences: L77890 AAB50174.1 Q92889

Publications (1)

1
Modulation of ERCC1-XPF Heterodimerization Inhibition via Structural Modification of Small Molecule Inhibitor Side-Chains. Claudia Weilbeer, David Jay, James C Donnelly, Francesco Gentile, Feridoun Karimi-Busheri, Xiaoyan Yang, Rajam S Mani, Yaping Yu, Ahmed H Elmenoufy, Khaled H Barakat, Jack A Tuszynski, Michael Weinfeld, Frederick G West. Frontiers in oncology. 2022 April;12:819172. [Full Text Article] [PubMed:35372043] [PMC:PMC8968952] Related Antibodies: LS-C173159.

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
ERCC4 / XPF (3)
No (3)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
ERCC4 / XPF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
104.3 kDa
20 µg/$215
ERCC4 / XPF Protein - Purified recombinant protein ERCC4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
104.3 kDa
20 µg/$1,107
ERCC4 / XPF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
104.3 kDa
100 µg/$710
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).