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ERCC2 / XPD

excision repair cross-complementing rodent repair deficiency, complementation group 2

ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.

Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 2
Synonyms: ERCC2, COFS2, EM9, XPD, TFIIH p80, BTF2 p80, TTD, XPDC, CXPD, TFIIH 80 kDa subunit
Target Sequences: NM_000400 CAA36463.1 P18074

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Products
Antibodies (37)
Primary (37)
ERCC2 / XPD (37)
Human (35)
Mouse (10)
Rat (6)
Bat (3)
Bovine (3)
Chimpanzee (3)
Drosophila (3)
Guinea pig (3)
Hamster (3)
Monkey (3)
Pig (3)
Xenopus (3)
Zebrafish (3)
IHC (4)
IHC-P (2)
WB (34)
ELISA (8)
ICC (1)
IF (4)
IP (2)
Peptide-ELISA (2)
rabbit (31)
mouse (6)
IgG (16)
IgG1 (1)
IgG1,k (1)
IgG2a (2)
IgG2b (1)
monoclonal mc (5)
polyclonal pc (32)
4G2-2A6 (1)
OTI4B11 (2)
APC (1)
APC Conjugated (2)
Biotin Conjugated (3)
Carrier-free (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (22)
aa404-637 (8)
N-Terminus (4)
aa1-300 (2)
aa78-307 (2)
C-Terminus (1)
aa687-722 (1)
aa710-760 (1)
No (37)
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
0.1 mg/$379
ERCC2 / XPD Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal (aa1-300) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$351
ERCC2 / XPD Antibody - Immunofluorescence analysis of HeLa cells.
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ERCC2 / XPD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ERCC2 / XPD Antibody
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321
ERCC2 / XPD Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
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ERCC2 / XPD Rabbit anti-Human Polyclonal (aa1-300) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ERCC2 / XPD Antibody - ERCC2 monoclonal antibody (M01), clone 4G2-2A6 Western Blot analysis of ERCC2 expression in HeLa NE.
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ERCC2 / XPD Mouse anti-Human Monoclonal (4G2-2A6) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
ERCC2 / XPD Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal (aa710-760) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ERCC2 / XPD Antibody - Anti-ERCC2 Antibody at 1:1000 dilution + K562 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 87 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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ERCC2 / XPD Rabbit anti-Human Polyclonal (aa687-722) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
ERCC2 / XPD Antibody - Western blot analysis of ERCC2 using A549 whole cells lysates
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ERCC2 / XPD Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ERCC2 / XPD Antibody - Human recombinant protein fragment corresponding to amino acids 78-307 of human ERCC2 (NP_000391) produced in E.coli.
Select
ERCC2 / XPD Mouse anti-Human Monoclonal (aa78-307) (OTI4B11) Antibody
Human
WB
Unconjugated
100 µl/$434
ERCC2 / XPD Antibody - Human recombinant protein fragment corresponding to amino acids 78-307 of human ERCC2. (NP_000391) produced in E.coli.
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ERCC2 / XPD Mouse anti-Human Monoclonal (aa78-307) (Carrier-free) (OTI4B11) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
Select
ERCC2 / XPD Mouse Monoclonal Antibody
ELISA
Unconjugated
150 µg/$842
Select
ERCC2 / XPD Mouse Monoclonal Antibody
ELISA
Unconjugated
150 µg/$842
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ERCC2 / XPD Antibody - ERCC2 / XPD antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ERCC2 / XPD Antibody - Western blot of ERCC2 / XPD antibody.
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal (aa404-637) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
ERCC2 / XPD Antibody - Western blot analysis of extracts of various cell lines, using ERCC2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
ERCC2 / XPD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 37 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).