ERCC1

excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)

ERCC1 functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.

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Products

Proteins (12)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (5)

Recombinant (6)

Target

ERCC1 (12)

Publications

No (12)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (3)

Myc-DDK (Flag) (6)

Species

Human (10)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (6)

Wheat Germ Extract (2)

Purification

Purified (3)

Supernatant (1)

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Human ERCC1 Protein (Recombinant His) - LS-G1766

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human ERCC1 Protein (Recombinant GST, N-terminus) (aa207-281) - LS-G58480

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ERCC1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72962

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.4 kDa

Price:

20 µg/$1,107

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Human ERCC1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72963

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.4 kDa

Price:

20 µg/$1,107

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Human ERCC1 Protein (Over-Expression Cell Culture Supernatant His, N-Terminal) (Asp2-Pro297) - LS-G97056

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~33 kDa

Price:

200 µl/$283

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Human ERCC1 Protein (Recombinant His, N-Terminal) (Asp2-Pro297) - LS-G97057

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

40 kDa

Price:

10 µg/$265; 100 µg/$365; 50 µg/$315

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Human ERCC1 Protein (Over-Expression Lysate His, N-Terminal) (Asp2-Pro297) - LS-G97061

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~33 kDa

Price:

100 µg/$298

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Human ERCC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G94048

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.4 kDa

Price:

20 µg/$150

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Human ERCC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G94049

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.4 kDa

Price:

20 µg/$150

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Human ERCC1 Protein (Recombinant GST) (Full Length) - LS-G28377

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62 kDa

Price:

10 µg/$479; 25 µg/$670

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ERCC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118259

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.4 kDa

Price:

100 µg/$494

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ERCC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103134

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.4 kDa

Price:

100 µg/$494

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